A recent study reveals that people who discontinue new slimming jabs like Wegovy and Mounjaro may regain reduced body mass far faster than those who end traditional diet and exercise programs.
Published data in a leading medical journal demonstrates that while overweight individuals can lose substantial amounts of their total mass while using the jabs, the mass is regained at an estimated rate of nearly a kilo each month after stopping.
"Individuals buying such medications must be informed of the risk of rapid weight regain when the treatment is stopped," cautioned lead investigator Dr. Susan Jebb.
This pace of regain suggests a return to pre-treatment weight in about 18 months.
Analyzing Therapies
The research, which looked at 37 of trials involving over 9,000 of patients, contrasted the outcomes of these new drugs with conventional dieting.
Researchers emphasize that people who shed pounds through dieting usually see a less rapid weight regain—approximately 0.1 kg a month—after stopping.
The Reason for the Fast Rebound
Experts propose the mode of action of the drugs accounts for the heightened rebound.
These medications copy a natural hormone called glucagon-like peptide-1, which moderates hunger.
"Artificially providing GLP-1 levels far above than normal might result in the system to generate a reduced amount of its endogenous GLP-1, and may also reduce sensitivity to its actions," noted Dr. Adam Collins, a dietetics researcher.
"Discontinuation of this medication means hunger is uncontrolled, making binge eating far more likely."
A Chronic Issue?
Health authorities suggest the injections for individuals with obesity-related medical conditions, accompanied by recommended diet and exercise modifications.
A number of clinicians argue that, considering the high risk of relapse, the treatment should be considered ongoing.
This perspective is supported by drug manufacturers, who state that the findings "underscore the chronic nature of excess weight," similar to managing diseases like high blood pressure.
User Accounts
People who have come off the medication describe a sudden return of hunger.
"It was like something that goes on and I was suddenly ravenous," said an individual.
This challenge is worsened if patients have not established sustainable lifestyle or habit changes during treatment.
Significant Interest
Figures suggest that millions of people in the UK have tried these injections in the last 12 months, with desire remaining high.
- Adoption is more common among women compared to males.
- The middle-aged age group shows the highest usage rates.
- Many obtain the medications through private prescriptions rather than public health services.
In conclusion, experts emphasize that while the jabs are effective tools for weight loss, they are not a magic cure and long-term success likely depends on combined lifestyle changes.
